Cycling Genes

Of the 800 cell cycle regulated genes, our algorithm identified 56 genes as differentially expressed with a p-value <.005. Below we provide links to a file contianing the list of 56 genes identified, as well as to figures in which the expression of these genes under wild type condition is compared to their expression in the fkh1/2 knockout experiment. In addition, for each of these genes we list which of the four relevant factors (fkh1, fkh2, ace2 and swi5) binds it. In the paper we show that all of these factors bind a significant subset of the identified genes, indicating that the set identified agrees with the independent binding experiment.

  • The list of the 56 identified genes (including binding information).
  • In the following figures the p-value appears on the top left side and the gene (or orf) name appears on the top right side of the figure. The blue curve represents the expression of the gene in the wild type experiment, and the red curve represents the expression in the knockout experiment.

  • Figures for the 16 genes that were the most significantly changed.
  • Figures for the next 16 genes (17-32).
  • Figures for the next 16 genes (33-48).
  • Figures for the last 8 genes (49-56).