Modules
Our algorithm discovered 106 modules ranging in size from five
(the minimum allowed) to 52 genes (a large set of co-
expressed ribosomal genes). The modules contained 655
distinct genes and were regulated by 68 of the 106
transcription factors. To determine the biological
significance of the modules generated, we looked at the
extent to which genes in the same module belonged to an
identical MIPS sub-category. Statistics were computed using
the hyper-geometric distribution and p-values were
determined.
Below we provide a link to a tab delimited file that contains the
modules that where found by our algorithm. For each module,
the top row lists the set of factors that regulate this module, and the
second row contains the average pairwise expression similarity (across
all 500 experiments) between the genes that belong to this module.
Next, the list of genes that belong to this module is presented,
where each gene is described by its orf name, its name and the description
that MIPS contains for this gene.
Following the list of genes, there are (at most) three lines
containing the different
MIPS subcategories that significantly overlap with
the set of genes in that module. We list the subcategory number
and name, and the p-value that was computed for this module with
this subcategory. A tab delimited file containing the module that where
found can be downloaded from here.
You can also view a
html version
of the same file. This version contains links for each of the orfs to its
website on SGD.